"The average dialysis patient undergoing three times weekly hemodialysis treatment is exposed to around 24,000 liters of dialysis fluid per annum."[Hoenich, Levin and Ronco, How Do Changes in Water Quality and Dialysate Composition Affect Clinical Outcomes? Blood Purif 2009;27:11-15 ]
The Nephros Dual Stage Ultrafilter has a .005 micron pore size and will allow you to comply with the proposed levels of filtration (see chart below). The Nephros DSU is an FDA 510k approved ultrafilter and has a performance life of up to 12 months, post-RO, with frequent use. The DSU is capable of removing endotoxins, as well as; Legionella, Pseudomonas, Stenotrophomonas, Acinetobacter, Klebsiella and Mycobacterium.
Potential areas of use include:
AAMI Standards (adopted on 1/26/11)
Field Tests and Installation Data
Field testing Portable RO
Ultrapure Water / Dialysis
How Do Changes in Water Quality and Dialysate Composition Affect Clinical Outcomes?
Ultra Pure Water free of endotoxins and bacteria for Dialysis Center Applications.
Ultrapure Dialysate:What is it and should everybody have it?
Ultrapure Dialysate Reduces Plasma Levels of ß2-Microglobulin and Pentosidine in Hemodialysis Patients
Inflammation and dialysate quality
Dialysate related cytokine induction and response to recombinant human erythropoietin in haemodialysis patients
Water Treatment / Biofilm / Endotoxins
Clinical Effect of Purification of Dialysis Fluids, Evidence and Experience
F-FC312 Dialysate Endotoxin Level and Mortality of Hemodialysis Patients in the United States Based on the DOPPS
Water treatment and monitor disinfection
Biofilm in dialysis water systems
Improvement of Anemia in Hemodialysis Patients Treated by Hemodiafiltration with High-Volume On-Line-Prepared Substituion Fluid
The relevance of convection in clinical practice: A critical review of the literature