Biologically Safe Water Filters

Following installation of the Nephros DSU, we recommend disinfecting the lines downstream of the DSU as per standard clinical procedure.  The DSU is compatible with most common water loop disinfection chemicals.  It can be subject to 1% Renalin, 1% bleach, 2% vinegar or heat disinfection (80°C for 1 hr) for 1 year of weekly exposures with no degradation in safety or efficacy.  Be aware, current filters supplied by dialysis machine manufacturers can be degraded by multiple bleach disinfections.

Disinfection should be carried out as per standard clinic procedures.  No special precautions or procedures are required for the DSU.  It is to be treated simply as an extension of the water distribution system.  Ongoing endotoxin testing should be performed according to your facility’s procedure.

Following chemical disinfection, the water must be tested for residual disinfectant with test strips or other means.  The increase in the water system surface area and volume due to the DSU may require longer rinsing times.

The pressure drop across the DSU generally reduces the flow rate by about 1/3 to 1/2 of the rate without the filter.  The filter should operate under normal use with minimal degradation in flow.  If the flow rate degrades significantly, replace the filter.

The installation of a Nephros DSU on your dialysis water system will help reduce your disinfection frequency.  The DSU .005 micron filter produces ultrapure water and attains high flow rates (2.5 gallons/min).  The filters are fast and simple to install, since they attach to quick-connect fittings (CPC).  The DSU can be installed post RO, on the RO loop or at the wall box and is an easy way to reduce water bacteria counts.

Additional studies and pictures of installations (click here).