Endotoxin Control for Portable RO’s

Dec 31 2009

Published by admin at 3:35 pm under Dialysis, Ultrapure water, Water filtration, medical water filters

Many acute dialysis units struggle to keep their portable RO/DI water supply for dialysis machines from exceeding the AAMI endotoxin standards.

Special considerations for acute hemodialysis have been issued. You can find these standards at the following link ANSI/AAMI RD52:2004 Dialysate for hemodialyzers . The following are found under amendment 3 - Annex E.

E.2 Fluid Quality: suggests achieving higher fluid quality by passing final dialysate through a bacteria-and endotoxin-retentive filter.

E.3.7 Endotoxin-retentive filters: recommends in-line dialysate filters as a final barrier against contamination of the dialysate.

E.4 Microbial control strategies: “Consideration should be given to installing an in-line dialysate filter in the dialysis machine, if the machine manufacturer allows that option.”

The Nephros DSU contains a .005 micron membrane which eliminates bacteria, viral agents, cysts, fungi and biological endotoxins. The DSU will produce ultrapure water when used post RO/DI.